Minority HIV-1 Drug Resistance Mutations and the Risk of NNRTI-based Antiretroviral Treatment Failure: A Systematic Review and Pooled Analysis

CONTEXT: Evidence regarding the impact of minority, or low frequency, HIV-1 drug-resistant variants on the effectiveness of first-line antiretroviral treatment (ART) is conflicting. OBJECTIVE: To evaluate the association of pre-existing HIV-1 minority drug-resistant variants with risk of first-line...

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Detalhes bibliográficos
Main Authors: Li, Jonathan Z., Paredes, Roger, Ribaudo, Heather, Svarovskaia, Evguenia S., Metzner, Karin J., Kozal, Michael J., Hullsiek, Kathy Huppler, Balduin, Melanie, Jakobsen, Martin R., Geretti, Anna Maria, Thiebaut, Rodolphe, Ostergaard, Lars, Masquelier, Bernard, Johnson, Jeffrey A., Miller, Michael D., Kuritzkes, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325645/
https://ncbi.nlm.nih.gov/pubmed/21467286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2011.375
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