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Overexpression of Dickkopf-3 induces apoptosis through mitochondrial pathway in human colon cancer

AIM: To investigate the mechanisms of the biological roles of Dickkopf-3 (Dkk-3) in cell invasion, survival and apoptosis in colon cancer cells. METHODS: Three human colon cancer cell lines, i.e., HT-29, LoVo and SW480, were used. Overexpression of Dkk-3 induced by pEGFP-N1-Dkk-3-GFP plasmid in LoVo...

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Detalhes bibliográficos
Main Authors: Yang, Zi-Rong, Dong, Wei-Guo, Lei, Xiao-Fei, Liu, Meng, Liu, Qi-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325524/
https://ncbi.nlm.nih.gov/pubmed/22529687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i14.1590
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