The Effect of Concurrent Substance Use Disorder on the Effectiveness of Single and Combination Antidepressant Medications for the Treatment of Major Depression: An Exploratory Analysis of a Single-Blind Randomized Trial

BACKGROUND: The co-occurrence of substance use disorder (SUD) and major depressive disorder (MDD) is common and is often thought to impair response to antidepressant therapy. These patients are often excluded from clinical trials, resulting in a significant knowledge gap regarding optimal pharmacoth...

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Detalhes bibliográficos
Main Authors: Davis, Lori L., Pilkinton, Patricia, Wisniewski, Stephen R., Trivedi, Madhukar H., Gaynes, Bradley, Howland, Robert H., Zisook, Sidney, Balasubramani, G.K., Fava, Maurizio, Rush, A. John
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325509/
https://ncbi.nlm.nih.gov/pubmed/22495941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/da.20918
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