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Cerebrovascular Cyclooxygenase-1 Expression, Regulation, and Role in Hypothalamic-Pituitary-Adrenal Axis Activation by Inflammatory Stimuli

Systemic injection of lipopolysaccharide (LPS) is a widely used model of immune/inflammatory challenge, which can invoke a host of CNS responses, including activation of the hypothalamic-pituitary-adrenal (HPA) axis. Inducible vascular prostaglandin E(2) (PGE(2)) synthesis by endothelial (ECs) and/o...

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Detalhes bibliográficos
Main Authors: García-Bueno, Borja, Serrats, Jordi, Sawchenko, Paul E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325493/
https://ncbi.nlm.nih.gov/pubmed/19828811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2373-09.2009
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