Delayed Toxicity Associated with Soluble Anthrax Toxin Receptor Decoy-Ig Fusion Protein Treatment

Soluble receptor decoy inhibitors, including receptor-immunogloubulin (Ig) fusion proteins, have shown promise as candidate anthrax toxin therapeutics. These agents act by binding to the receptor-interaction site on the protective antigen (PA) toxin subunit, thereby blocking toxin binding to cell su...

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Bibliographic Details
Main Authors: Thomas, Diane, Naughton, John, Cote, Christopher, Welkos, Susan, Manchester, Marianne, Young, John A. T.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325282/
https://ncbi.nlm.nih.gov/pubmed/22511955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034611
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