A Caprine Herpesvirus 1 Vaccine Adjuvanted with MF59™ Protects against Vaginal Infection and Interferes with the Establishment of Latency in Goats

The immunogenicity and the efficacy of a beta-propiolactone-inactivated caprine herpesvirus 1 (CpHV-1) vaccine adjuvanted with MF59™ were tested in goats. Following two subcutaneous immunizations, goats developed high titers of CpHV-1-specific serum and vaginal IgG and high serum virus neutralizatio...

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Main Authors: Marinaro, Mariarosaria, Rezza, Giovanni, Del Giudice, Giuseppe, Colao, Valeriana, Tarsitano, Elvira, Camero, Michele, Losurdo, Michele, Buonavoglia, Canio, Tempesta, Maria
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325274/
https://ncbi.nlm.nih.gov/pubmed/22511971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034913
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