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Exploiting evolution to treat drug resistance: Combination therapy and the double bind

Although many anticancer therapies are successful in killing a large percentage of tumour cells when initially administered, the evolutionary dynamics underpinning tumour progression mean that often, resistance is an inevitable outcome. Research in the field of ecology suggests that an evolutionary...

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Detalhes bibliográficos
Main Authors: Basanta, David, Gatenby, Robert A., Anderson, Alexander R. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325107/
https://ncbi.nlm.nih.gov/pubmed/22369188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp200458e
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