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The rejoining of double-strand breaks in DNA by human cell extracts.

A double-strand DNA break was introduced at a specific site within the lacZ gene of plasmid pUC18 using one of several restriction enzymes, and the plasmid exposed to nuclear extracts from human cell lines. Physical rejoining of DNA was monitored by Southern analysis after gel separation, and the fi...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: North, P, Ganesh, A, Thacker, J
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 1990
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332482/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2243768/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.21.6205
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