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Coordination between TLR9 Signaling in Macrophages and CD3 Signaling in T cells Induces Robust Expression of IL30

Interleukin 30 (IL30), the p28 subunit of IL27, interacts with Epstein-Barr virus induced gene 3 to form IL27, which modulates both pro- and anti-inflammatory responses during autoimmune or infectious disease. It also acts as a natural antagonist of glycoprotein 130 (gp130), thereby attenuating the...

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Bibliographic Details
Main Authors: Dibra, Denada, Cutrera, Jeffry J., Li, Shulin
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324657/
https://ncbi.nlm.nih.gov/pubmed/22407920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100883
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