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Metformin-mediated Bambi expression in Hepatic Stellate Cells induces pro-survival Wnt/β-catenin signaling

Adenosine monophosphate-activated protein kinase (AMPK) regulates lipid, cholesterol and glucose metabolism in specialized metabolic tissues, such as muscle, liver and adipose tissue. Agents that activate AMPK, such as metformin and AICAR, have beneficial effects on liver glucose and lipid metabolis...

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Detalhes bibliográficos
Main Authors: Subramaniam, Nanthakumar, Sherman, Mara H., Rao, Renuka, Wilson, Caroline, Coulter, Sally, Atkins, Annette R., Evans, Ronald M, Liddle, Christopher, Downes, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324648/
https://ncbi.nlm.nih.gov/pubmed/22406377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-12-0053
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