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PGE(2) produced by the lung augments the effector phase of allergic inflammation
Elevated PGE(2) is a hallmark of most inflammatory lesions. This lipid mediator can induce the cardinal signs of inflammation, and the beneficial actions of non-steroidal anti-inflammatory drugs are attributed to inhibition of cyclooxygenase COX-1 and COX-2, enzymes essential in the biosynthesis of...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3324636/ https://ncbi.nlm.nih.gov/pubmed/22412193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101873 |
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