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Miz1 Is a Critical Repressor of cdkn1a during Skin Tumorigenesis

The transcription factor Miz1 forms repressive DNA-binding complexes with the Myc, Gfi-1 and Bcl-6 oncoproteins. Known target genes of these complexes encode the cyclin-dependent kinase inhibitors (CKIs) cdkn2b (p15(Ink4)), cdkn1a (p21(Cip1)), and cdkn1c (p57(Kip2)). Whether Miz1-mediated repression...

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書誌詳細
主要な著者: Hönnemann, Jan, Sanz-Moreno, Adrián, Wolf, Elmar, Eilers, Martin, Elsässer, Hans-Peter
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324535/
https://ncbi.nlm.nih.gov/pubmed/22509363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034885
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