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An Epithelial Serine Protease, AgESP, Is Required for Plasmodium Invasion in the Mosquito Anopheles gambiae

BACKGROUND: Plasmodium parasites need to cross the midgut and salivary gland epithelia to complete their life cycle in the mosquito. However, our understanding of the molecular mechanism and the mosquito genes that participate in this process is still very limited. METHODOLOGY/PRINCIPAL FINDINGS: We...

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Bibliographic Details
Main Authors: Rodrigues, Janneth, Oliveira, Giselle A., Kotsyfakis, Michalis, Dixit, Rajnikant, Molina-Cruz, Alvaro, Jochim, Ryan, Barillas-Mury, Carolina
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324419/
https://ncbi.nlm.nih.gov/pubmed/22509400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035210
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