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Spontaneous Eosinophilic Nasal Inflammation in a Genetically-Mutant Mouse: Comparative Study with an Allergic Inflammation Model

BACKGROUND: Eosinophilic inflammation is a hallmark of chronic rhinosinusitis with nasal polyps. To model this disease process experimentally, nasal sensitization of mice with ovalbumin or aspergillus has been described. Here, we describe a genetically mutant mouse that develops robust spontaneous n...

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Detalles Bibliográficos
Autores principales: Cho, Seok Hyun, Oh, Sun Young, Zhu, Zhou, Lee, Joan, Lane, Andrew P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324406/
https://ncbi.nlm.nih.gov/pubmed/22509389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035114
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