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Structure of melanoma inhibitory activity protein, a member of a recently identified family of secreted proteins

Melanoma inhibitory activity (MIA) is a 12-kDa protein that is secreted from both chondrocytes and malignant melanoma cells. MIA has been reported to have effects on cell growth and adhesion, and it may play a role in melanoma metastasis and cartilage development. We report the 1.4-Å crystal structu...

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Библиографические подробности
Главные авторы: Lougheed, Julie C., Holton, James M., Alber, Tom, Bazan, J. Fernando, Handel, Tracy M.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 2001
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC33244/
https://ncbi.nlm.nih.gov/pubmed/11331761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.091601698
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