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The central mechanism underlying hypertension: a review of the roles of sodium ions, epithelial sodium channels, the renin–angiotensin–aldosterone system, oxidative stress and endogenous digitalis in the brain

The central nervous system has a key role in regulating the circulatory system by modulating the sympathetic and parasympathetic nervous systems, pituitary hormone release, and the baroreceptor reflex. Digoxin- and ouabain-like immunoreactive materials were found >20 years ago in the hypothalamic...

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Detalhes bibliográficos
Main Authors: Takahashi, Hakuo, Yoshika, Masamichi, Komiyama, Yutaka, Nishimura, Masato
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324327/
https://ncbi.nlm.nih.gov/pubmed/21814209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hr.2011.105
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