A randomized, double-blind, placebo-controlled trial of antidepressants in Parkinson disease

OBJECTIVE: To evaluate the efficacy and safety of a selective serotonin reuptake inhibitor (SSRI) and a serotonin and norepinephrine reuptake inhibitor (SNRI) in the treatment of depression in Parkinson disease (PD). METHODS: A total of 115 subjects with PD were enrolled at 20 sites. Subjects were r...

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Auteurs principaux: Richard, I.H., McDermott, M.P., Kurlan, R., Lyness, J.M., Como, P.G., Pearson, N., Factor, S.A., Juncos, J., Serrano Ramos, C., Brodsky, M., Manning, C., Marsh, L., Shulman, L., Fernandez, H.H., Black, K.J., Panisset, M., Christine, C.W., Jiang, W., Singer, C., Horn, S., Pfeiffer, R., Rottenberg, D., Slevin, J., Elmer, L., Press, D., Hyson, H.C., McDonald, W., Richard, Irene, McDonald, William, McDermott, Michael, Como, Peter G., Kurlan, Roger, Lyness, Jeffrey M., Pearson, Nancy, Sommerfeld, Barbara, Deeley, Cheryl, de la Torre, Tania, Barnard, Michele, Wilson, April, Lincoln, Maryann, Damgaard, Paula, Gerstenhaber, Melissa, Dustin, Kelly, Zappala, Nancy, Swartz, Camille, Creech, Mary, Shipley, Elda, Blankenship, Samantha, Beland, Monica, Roth, Jessie, Burnette, Heather, Foxworth, Tamara, Quesada, Monica, Lloyd, Mary, Pfeiffer, Brenda, Hansen, Joy, Folie, Joy, Wagner, Renee, Spears, Julia, Taylor, Colleen, Brown, Rachel, Iguchi, Lisa, Lim, Chen, LaDonna, Kori, Megens, Julie, Menza, Matthew, Cummings, Jeffrey, Hamer, Robert, Shannon, Kathleen, Odenkirchen, Joanne, Conwit, Robin, Beck, Christopher, LaDonna, Donna, Bausch, Jan, Kim, Scott, Chismar, Ron, Quinn, Sinead, Bean, Steve, Daigneault, Susan, Lindsay, Patricia, Ross, Tori, Kompoliti, Katie
Format: Artigo
Langue:Inglês
Publié: Lippincott Williams & Wilkins 2012
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324323/
https://ncbi.nlm.nih.gov/pubmed/22496199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3182516244
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