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Human γδ T lymphocytes induce robust NK cell–mediated antitumor cytotoxicity through CD137 engagement
Natural killer (NK) cells are innate effector lymphocytes that control the growth of major histocompatibility complex class I negative tumors. We show here that γδ T lymphocytes, expanded in vitro in the presence isopentenylpyrophosphate (IPP), induce NK cell–mediated killing of tumors that are usua...
Tallennettuna:
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society of Hematology
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3324253/ https://ncbi.nlm.nih.gov/pubmed/20519625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-234211 |
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