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Supercooling Agent Icilin Blocks a Warmth-Sensing Ion Channel TRPV3

Transient receptor potential vanilloid subtype 3 (TRPV3) is a thermosensitive ion channel expressed in a variety of neural cells and in keratinocytes. It is activated by warmth (33–39°C), and its responsiveness is dramatically increased at nociceptive temperatures greater than 40°C. Monoterpenoids a...

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Detalhes bibliográficos
Main Authors: Sherkheli, Muhammad Azhar, Gisselmann, Guenter, Hatt, Hanns
Formato: Artigo
Idioma:Inglês
Publicado em: The Scientific World Journal 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324214/
https://ncbi.nlm.nih.gov/pubmed/22548000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/2012/982725
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