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The essential role of AMPA receptor GluR2 subunit RNA editing in the normal and diseased brain

α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are comprised of different combinations of GluA1–GluA4 (also known asGluR1–GluR4 and GluR-A to GluR-D) subunits. The GluA2 subunit is subject to RNA editing by the ADAR2 enzyme, which converts a codon for glutamine (Gln; Q), prese...

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Autors principals: Wright, Amanda, Vissel, Bryce
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324117/
https://ncbi.nlm.nih.gov/pubmed/22514516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2012.00034
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