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Regulatory architecture determines optimal regulation of gene expression in metabolic pathways

In response to environmental changes, the connections (“arrows”) in gene regulatory networks determine which genes modulate their expression, but the quantitative parameters of the network (“the numbers on the arrows”) are equally important in determining the resulting phenotype. What are the object...

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Detalhes bibliográficos
Main Authors: Chubukov, Victor, Zuleta, Ignacio A., Li, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324031/
https://ncbi.nlm.nih.gov/pubmed/22416120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114235109
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