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Regulatory architecture determines optimal regulation of gene expression in metabolic pathways
In response to environmental changes, the connections (“arrows”) in gene regulatory networks determine which genes modulate their expression, but the quantitative parameters of the network (“the numbers on the arrows”) are equally important in determining the resulting phenotype. What are the object...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3324031/ https://ncbi.nlm.nih.gov/pubmed/22416120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114235109 |
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