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Selective esterase–ester pair for targeting small molecules with cellular specificity

Small molecules are important tools to measure and modulate intracellular signaling pathways. A longstanding limitation for using chemical compounds in complex tissues has been the inability to target bioactive small molecules to a specific cell class. Here, we describe a generalizable esterase–este...

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Главные авторы: Tian, Lin, Yang, Yunlei, Wysocki, Laura M., Arnold, Alma C., Hu, Amy, Ravichandran, Balaji, Sternson, Scott M., Looger, Loren L., Lavis, Luke D.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323987/
https://ncbi.nlm.nih.gov/pubmed/22411832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111943109
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