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Illegitimate and homologous recombination in mammalian cells: differential sensitivity to an inhibitor of poly(ADP-ribosylation).

We determined the effect of 3-methoxybenzamide (3-MB), a competitive inhibitor of poly(ADP-ribose)polymerase (E.C. 2.4.2.30), on illegitimate and extrachromosomal homologous recombination in mouse Ltk- cells. Cells were transfected with a wild type Herpes thymidine kinase (tk) gene or with two defec...

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Main Authors: Waldman, B C, Waldman, A S
Format: Artigo
Jezik:Inglês
Izdano: 1990
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC332394/
https://ncbi.nlm.nih.gov/pubmed/2172923
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