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A Screening Assay to Identify Agents That Enhance T-Cell Recognition of Human Melanomas

Although a series of melanoma differentiation antigens for immunotherapeutic targeting has been described, heterogeneous expression of antigens such as Melan-A/MART-1 and gp100 results from a loss of antigenic expression in many late stage tumors. Antigen loss can represent a means for tumor escape...

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Autori principali: Haggerty, Timothy J., Dunn, Ian S., Rose, Lenora B., Newton, Estelle E., Kurnick, James T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323935/
https://ncbi.nlm.nih.gov/pubmed/22085019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2011.0379
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