Sequence analysis of two temperature-sensitive mutations in the alpha subunit gene (rpoA) of Escherichia coli RNA polymerase.

The rpoA gene of Escherichia coli encodes the alpha subunit of the DNA-dependent RNA polymerase. Two mutant alleles, rpoA101 and rpoA112, both of which produce RNA polymerase with altered thermostability and reduced fidelity of transcription in vitro (Ishihama et al. (1980) J. Mol. Biol. 137, 137-15...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Igarashi, K, Fujita, N, Ishihama, A
Format: Artigo
Language:Inglês
Published: Oxford University Press 1990
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332388/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2235479/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.20.5945
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