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Effects of exogenous hydrogen sulphide on calcium signalling, background (TASK) K channel activity and mitochondrial function in chemoreceptor cells

It has been proposed that endogenous H(2)S mediates oxygen sensing in chemoreceptors; this study investigates the mechanisms by which H(2)S excites carotid body type 1 cells. H(2)S caused a rapid reversible increase in intracellular calcium with EC(50) ≈ 6 μM. This [Ca(2+)](i) response was abolished...

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Hlavní autor: Buckler, Keith J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323823/
https://ncbi.nlm.nih.gov/pubmed/22419174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-012-1089-8
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