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Roles of the N- and C-terminal sequences in Hsp27 self-association and chaperone activity

The small heat shock protein 27 (Hsp27 or HSPB1) is an oligomeric molecular chaperone in vitro that is associated with several neuromuscular, neurological, and neoplastic diseases. Although aspects of Hsp27 biology are increasingly well known, understanding of the structural basis for these involvem...

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Autors principals: Lelj-Garolla, Barbara, Mauk, A Grant
Format: Artigo
Idioma:Inglês
Publicat: Wiley Subscription Services, Inc., A Wiley Company 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323787/
https://ncbi.nlm.nih.gov/pubmed/22057845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.761
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