Iodoacetic acid, but not sodium iodate, creates an inducible swine model of photoreceptor damage

Our purpose was to find a method to create a large animal model of inducible photoreceptor damage. To this end, we tested in domestic swine the efficacy of two chemical toxins, known to create photoreceptor damage in other species: Iodoacetic Acid (IAA) and Sodium Iodate (NaIO(3)). Intravenous (IV)...

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Autores principales: Noel, Jennifer M., Fernandez de Castro, Juan P., DeMarco, Paul J., Franco, Luisa M., Wang, Wei, Vukmanic, Eric V., Peng, Xiaoyan, Sandell, Julie H., Scott, Patrick A., Kaplan, Henry J., McCall, Maureen A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323738/
https://ncbi.nlm.nih.gov/pubmed/22251455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2011.12.018
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