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Minocycline attenuates microglia activation and blocks the long-term epileptogenic effects of early-life seizures

Innate immunity mediated by microglia appears to play a crucial role in initiating and propagating seizure-induced inflammatory responses. To address the role of activated microglia in the pathogenesis of childhood epilepsy, we first examined the time course of microglia activation following kainic...

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Detalhes bibliográficos
Main Authors: Abraham, Jayne, Fox, Patrick D., Condello, Carlo, Bartolini, Alyssa, Koh, Sookyong
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323726/
https://ncbi.nlm.nih.gov/pubmed/22366182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.02.006
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