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Structure of geranyl diphosphate C-methyltransferase from Streptomyces coelicolor and implications for the mechanism of isoprenoid modification

Geranyl diphosphate C-methyltransferase (GPPMT) from Streptomyces coelicolor A3(2) is the first methyltransferase discovered that modifies an acyclic isoprenoid diphosphate, geranyl diphosphate (GPP), to yield a non-canonical acyclic allylic diphosphate product, 2-methylgeranyl diphosphate, which se...

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Détails bibliographiques
Auteurs principaux: Köksal, Mustafa, Chou, Wayne K. W., Cane, David E., Christianson, David W.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323675/
https://ncbi.nlm.nih.gov/pubmed/22455498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300109c
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