Spherical Lactic Acid Bacteria Activate Plasmacytoid Dendritic Cells Immunomodulatory Function via TLR9-Dependent Crosstalk with Myeloid Dendritic Cells

Plasmacytoid dendritic cells (pDC) are a specialized sensor of viral and bacterial nucleic acids and a major producer of IFN-α that promotes host defense by priming both innate and acquired immune responses. Although synthetic Toll-like receptor (TLR) ligands, pathogenic bacteria and viruses activat...

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Библиографические подробности
Главные авторы: Jounai, Kenta, Ikado, Kumiko, Sugimura, Tetsu, Ano, Yasuhisa, Braun, Jonathan, Fujiwara, Daisuke
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323594/
https://ncbi.nlm.nih.gov/pubmed/22505996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032588
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