Multiple Mitochondrial Introgression Events and Heteroplasmy in Trypanosoma cruzi Revealed by Maxicircle MLST and Next Generation Sequencing

BACKGROUND: Mitochondrial DNA is a valuable taxonomic marker due to its relatively fast rate of evolution. In Trypanosoma cruzi, the causative agent of Chagas disease, the mitochondrial genome has a unique structural organization consisting of 20–50 maxicircles (∼20 kb) and thousands of minicircles...

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Hauptverfasser: Messenger, Louisa A., Llewellyn, Martin S., Bhattacharyya, Tapan, Franzén, Oscar, Lewis, Michael D., Ramírez, Juan David, Carrasco, Hernan J., Andersson, Björn, Miles, Michael A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323513/
https://ncbi.nlm.nih.gov/pubmed/22506081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001584
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