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Strong association between mRNA folding strength and protein abundance in S. cerevisiae
One of the open questions in regulatory genomics is how the efficiency of gene translation is encoded in the coding sequence. Here we analyse recently generated measurements of folding energy in Saccharomyces cerevisiae, showing that genes with high protein abundance tend to have strong mRNA folding...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3323128/ https://ncbi.nlm.nih.gov/pubmed/22249164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.262 |
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