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Strong association between mRNA folding strength and protein abundance in S. cerevisiae

One of the open questions in regulatory genomics is how the efficiency of gene translation is encoded in the coding sequence. Here we analyse recently generated measurements of folding energy in Saccharomyces cerevisiae, showing that genes with high protein abundance tend to have strong mRNA folding...

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Autors principals: Zur, Hadas, Tuller, Tamir
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323128/
https://ncbi.nlm.nih.gov/pubmed/22249164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.262
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