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Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus
Inhibition of proliferation by cell-to-cell contact is essential for tissue organization, and its disruption contributes to tumorigenesis. The FERM domain protein Merlin, encoded by the NF2 tumour suppressor gene, is an important mediator of contact inhibition. Merlin was thought to inhibit mitogeni...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3323126/ https://ncbi.nlm.nih.gov/pubmed/22482125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.11 |
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