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Expression of a human O6-alkylguanine-DNA-alkyltransferase cDNA in human cells and transgenic mice.

A truncated human O6-alkylguanine-DNA-alkyltransferase (ATase) cDNA was ligated into an expression vector under the control of the mouse metallothionein-1 gene promotor and upstream of part of the human growth hormone gene to provide splice and polyadenylation signals. Transfection of this construct...

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Udgivet i:Nucleic Acids Res
Principais autores: Fan, C Y, Potter, P M, Rafferty, J, Watson, A J, Cawkwell, L, Searle, P F, O'Connor, P J, Margison, G P
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1990
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332306/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2216765/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.19.5723
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