Human Protein N-terminal Acetyltransferase hNaa50p (hNAT5/hSAN) Follows Ordered Sequential Catalytic Mechanism: COMBINED KINETIC AND NMR STUDY

N(α)-Acetylation is a common protein modification catalyzed by different N-terminal acetyltransferases (NATs). Their essential role in the biogenesis and degradation of proteins is becoming increasingly evident. The NAT hNaa50p preferentially modifies peptides starting with methionine followed by a...

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Hlavní autoři: Evjenth, Rune H., Brenner, Annette K., Thompson, Paul R., Arnesen, Thomas, Frøystein, Nils Åge, Lillehaug, Johan R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Enzymology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323058/
https://ncbi.nlm.nih.gov/pubmed/22311970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.326587
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