Structural Insights into Methyltransferase KsgA Function in 30S Ribosomal Subunit Biogenesis

The assembly of the ribosomal subunits is facilitated by ribosome biogenesis factors. The universally conserved methyltransferase KsgA modifies two adjacent adenosine residues in the 3′-terminal helix 45 of the 16 S ribosomal RNA (rRNA). KsgA recognizes its substrate adenosine residues only in the c...

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Bibliographic Details
Main Authors: Boehringer, Daniel, O'Farrell, Heather C., Rife, Jason P., Ban, Nenad
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Protein Synthesis and Degradation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323044/
https://ncbi.nlm.nih.gov/pubmed/22308031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.318121
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