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Propeptide of Aminopeptidase 1 Protein Mediates Aggregation and Vesicle Formation in Cytoplasm-to-Vacuole Targeting Pathway

Misfolded protein aggregation causes disease and aging; autophagy counteracts this by eliminating damaged components, enabling cells to survive starvation. The cytoplasm-to-vacuole targeting pathway in yeast encompasses the aggregation of the premature form of aminopeptidase 1 (prApe1) in cytosol an...

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Библиографические подробности
Главные авторы: Morales Quinones, Mariana, Winston, Jared T., Stromhaug, Per E.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323037/
https://ncbi.nlm.nih.gov/pubmed/22123825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.311696
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