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Multiple Forms of Spire-Actin Complexes and their Functional Consequences

Spire is a WH2 domain-containing actin nucleator essential for establishing an actin mesh during oogenesis. In vitro, in addition to nucleating filaments, Spire can sever them and sequester actin monomers. Understanding how Spire is capable of these disparate functions and which are physiologically...

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Autores principales: Chen, Christine K., Sawaya, Michael R., Phillips, Martin L., Reisler, Emil, Quinlan, Margot E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323035/
https://ncbi.nlm.nih.gov/pubmed/22334675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.317792
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