cAMP Induces Stromal Interaction Molecule 1 (STIM1) Puncta but neither Orai1 Protein Clustering nor Store-operated Ca(2+) Entry (SOCE) in Islet Cells

The events leading to the activation of store-operated Ca(2+) entry (SOCE) involve Ca(2+) depletion of the endoplasmic reticulum (ER) resulting in translocation of the transmembrane Ca(2+) sensor protein, stromal interaction molecule 1 (STIM1), to the junctions between ER and the plasma membrane whe...

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Bibliographic Details
Main Authors: Tian, Geng, Tepikin, Alexei V., Tengholm, Anders, Gylfe, Erik
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323006/
https://ncbi.nlm.nih.gov/pubmed/22298778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.292854
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