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Lack of Plakoglobin in Epidermis Leads to Keratoderma

Loss-of-function mutation of Jup has been associated with Naxos disease, which is characterized by arrhythmogenic cardiomyopathy and the cutaneous disorder palmoplantar keratoderma. Previously, we have shown that genetic ablation of Jup in cardiomyocytes in mice leads to arrhythmogenic cardiomyopath...

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Main Authors: Li, Deqiang, Zhang, Wenjun, Liu, Ying, Haneline, Laura S., Shou, Weinian
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322998/
https://ncbi.nlm.nih.gov/pubmed/22315228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.299669
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