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Hepatic Stellate Cell-derived Delta-like Homolog 1 (DLK1) Protein in Liver Regeneration

Hepatic stellate cells (HSCs) undergo myofibroblastic activation in liver fibrosis and regeneration. This phenotypic switch is mechanistically similar to dedifferentiation of adipocytes as such the necdin-Wnt pathway causes epigenetic repression of the master adipogenic gene Pparγ, to activate HSCs....

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Autors principals: Zhu, Nian-Ling, Asahina, Kinji, Wang, Jiaohong, Ueno, Akiko, Lazaro, Raul, Miyaoka, Yuichiro, Miyajima, Atsushi, Tsukamoto, Hidekazu
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322997/
https://ncbi.nlm.nih.gov/pubmed/22298767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.312751
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