Loss of Transcription Factor Nuclear Factor-Erythroid 2 (NF-E2) p45-related Factor-2 (Nrf2) Leads to Dysregulation of Immune Functions, Redox Homeostasis, and Intracellular Signaling in Dendritic Cells

Dendritic cells (DCs) are critical mediators of immunity and immune tolerance by orchestrating multiple aspects of T cell activation and function. Immature DCs (iDCs) expressing low levels of co-stimulatory receptors are highly efficient at antigen capture but are poor activators of T cells. Maturat...

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Main Authors: Yeang, Han Xian Aw, Hamdam, Junnat M., Al-Huseini, Laith M. A., Sethu, Swaminathan, Djouhri, Laiche, Walsh, Joanne, Kitteringham, Neil, Park, B. Kevin, Goldring, Christopher E., Sathish, Jean G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322986/
https://ncbi.nlm.nih.gov/pubmed/22311972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.322420
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