The association of statins and taxanes: an efficient combination trigger of cancer cell apoptosis

BACKGROUND: Cancer cell killing might be achieved by the combined use of available drugs. Statins are major anti-hypercholesterolemia drugs, which also trigger apoptosis of many cancer cell types, while docetaxel is a potent microtubule-stabilising agent. METHODS: Here, we looked at the combined eff...

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Detalhes bibliográficos
Main Authors: Follet, J, Corcos, L, Baffet, G, Ezan, F, Morel, F, Simon, B, Le Jossic-Corcos, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322964/
https://ncbi.nlm.nih.gov/pubmed/22294184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.6
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