Uptake of risk-reducing salpingo-oophorectomy in women carrying a BRCA1 or BRCA2 mutation: evidence for lower uptake in women affected by breast cancer and older women

BACKGROUND: Bilateral risk-reducing salpingo-oophorectomy (BRRSO) is the only effective way of reducing mortality from ovarian cancer. This study investigates uptake of BRRSO in 700 BRCA1/2 mutation carriers from Greater Manchester. METHODS: Dates of last follow-up and BRRSO were obtained, and the f...

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Bibliographic Details
Main Authors: Sidon, L, Ingham, S, Clancy, T, Clayton, R, Clarke, A, Jones, E A, Lalloo, F, Evans, D G R
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
Subjects:
Genetics and Genomics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322942/
https://ncbi.nlm.nih.gov/pubmed/22187038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.573
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