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Undersulfation of Heparan Sulfate Restricts Differentiation Potential of Mouse Embryonic Stem Cells

Heparan sulfate proteoglycans, present on cell surfaces and in the extracellular matrix, interact with growth factors and morphogens to influence growth and differentiation of cells. The sulfation pattern of the heparan sulfate chains formed during biosynthesis in the Golgi compartment will determin...

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Autori principali: Forsberg, Maud, Holmborn, Katarina, Kundu, Soumi, Dagälv, Anders, Kjellén, Lena, Forsberg-Nilsson, Karin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322844/
https://ncbi.nlm.nih.gov/pubmed/22298785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.337030
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