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Undersulfation of Heparan Sulfate Restricts Differentiation Potential of Mouse Embryonic Stem Cells

Heparan sulfate proteoglycans, present on cell surfaces and in the extracellular matrix, interact with growth factors and morphogens to influence growth and differentiation of cells. The sulfation pattern of the heparan sulfate chains formed during biosynthesis in the Golgi compartment will determin...

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Detalles Bibliográficos
Main Authors: Forsberg, Maud, Holmborn, Katarina, Kundu, Soumi, Dagälv, Anders, Kjellén, Lena, Forsberg-Nilsson, Karin
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322844/
https://ncbi.nlm.nih.gov/pubmed/22298785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.337030
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