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Intracellular linkers are involved in Mg(2+)-dependent modulation of the Eag potassium channel

Modulation of activation kinetics by divalent ions is one of the characteristic features of Eag channels. Here, we report that Mg(2+)-dependent deceleration of Eag channel activation is significantly attenuated by a G297E mutation, which exhibits a gain-of-function phenotype in Drosophila by suppres...

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Detalhes bibliográficos
Main Authors: Liu, Xinqiu, Wu, Yuying, Zhou, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322480/
https://ncbi.nlm.nih.gov/pubmed/20855938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.4.4.12329
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