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Growth of Limb Muscle is Dependent on Skeletal-Derived Indian Hedgehog

During embryogenesis, muscle and bone develop in close temporal and spatial proximity. We show that Indian Hedgehog, a bone-derived signaling molecule, participates in growth of skeletal muscle. In Ihh(−/−) embryos, skeletal muscle development appears abnormal at embryonic day 14.5 and at later ages...

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Bibliographic Details
Main Authors: Bren-Mattison, Yvette, Hausburg, Melissa, Olwin, Bradley B.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322465/
https://ncbi.nlm.nih.gov/pubmed/21683695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.06.002
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