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ALK and MYCN: when two oncogenes are better than one
Mutations of ALK are frequently observed in MYCN-amplified neuroblastomas and correlate with poor clinical outcome, but how these oncogenes cooperate in neuroblastoma development remains unclear. In this issue of Cancer Cell, Zhu et al. describe a mechanism by which ALK and MYCN synergistically indu...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3322412/ https://ncbi.nlm.nih.gov/pubmed/22439928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.03.004 |
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