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M2 Protein from Influenza A: From multiple structures to biophysical and functional insights
The M2 protein from influenza A is a proton channel as a tetramer, with a single transmembrane helix from each monomer lining the pore. Val27 and Trp41 form gates at either end of the pore and His37 mediates the shuttling of protons across a central barrier between the N- and C-terminal aqueous pore...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3322387/ https://ncbi.nlm.nih.gov/pubmed/22482709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2012.01.005 |
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